What is ICSI?
By: David S. Karabinus, PhD, HCLD
ICSI, pronounced "Ick-See", is an acronym for Intra-Cytoplasmic Sperm Injection, a microscopic procedure where a single sperm is injected into an egg. Normally for a sperm to fertilize an egg, a sperm has to swim to the egg, penetrate the cells surrounding the egg, penetrate the covering of the egg, and penetrating egg cell membrane. ICSI does all this work for the sperm to make sure the sperm DNA is delivered to the egg. ICSI is performed in circumstances when the number of sperm is insufficient for fertilization to reliably occur, when the sperm's ability to fertilize the egg is impaired, or when the egg is known to resist sperm penetration. ICSI does not require the use of ejaculated sperm; sperm surgically retrieved from the testes or epididymides may be used. Before the development of ICSI, donor sperm, adoption, or childlessness were the only options for men who produced low numbers of sperm or functionally impaired sperm.
ICSI, pronounced "Ick-See", is an acronym for Intra-Cytoplasmic Sperm Injection, a microscopic procedure where a single sperm is injected into an egg. Normally for a sperm to fertilize an egg, a sperm has to swim to the egg, penetrate the cells surrounding the egg, penetrate the covering of the egg, and penetrating egg cell membrane. ICSI does all this work for the sperm to make sure the sperm DNA is delivered to the egg. ICSI is performed in circumstances when the number of sperm is insufficient for fertilization to reliably occur, when the sperm's ability to fertilize the egg is impaired, or when the egg is known to resist sperm penetration. ICSI does not require the use of ejaculated sperm; sperm surgically retrieved from the testes or epididymides may be used. Before the development of ICSI, donor sperm, adoption, or childlessness were the only options for men who produced low numbers of sperm or functionally impaired sperm.
posted by Kathleen, Contributing Editor at
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