Assisted Hatching, a common procedure performed during an IVF cycle in which the zona pellucida (ZP- outer layer of the egg) is thinned or breached, was the subject of a recent scientific
study. 121 women were involved in the randomized, double blind study, which was published in the Journal
Fertility and Sterility. The women were younger than 38 years and had embryos with a ZP thickness of ≥13μm. Rates of clinical pregnancy, implantation and live births were compared. Surprisingly, the results showed no significant differences between the group that had the hatching procedure and the control group.
Previous studies have had conflicting results. According to the Society for Assisted Reproductive Technology and the American Society for Reproductive Medicine, the procedure is still considered useful in cases with a poor prognosis. Women with previous history of ≥2 IVF failures, poor quality embryos, and women aged ≥38 years should be considered candidates for assisted hatching.